Furazolidone: features of use in children. Furazolidone for children: instructions for use Furazolidone for children 4 years old dosage

Furazolidone refers to antibacterial agents and is used to combat poisoning. It is effective for infections of the genitourinary system, gastrointestinal tract and giardiasis. Unanimously recognized by physicians as a safe and effective drug, Furazolidone is approved for use in the treatment of poisoning in children of various ages. What is the drug and in what cases can children use Furazolidone, we will talk.

Furazolidone is a drug from the group of nitrofurans with antibacterial properties.

Description of Furazolidone

Furazolidone belongs to the group of nitrofurans, which have a devastating effect on the life processes of pathogenic microbes. The working substance is furazolidone, which gave the name to the agent. In addition, it contains lactose monohydrate, calcium stearate, silicon dioxide, potato starch.

Produced in the form of tablets (pellets) and granules; on the packaging, as a rule, the content of the main substance is indicated. For example, Furazolidone 50 means that 50 mg of the active ingredient is present in one tablet. The drug is inexpensive: one blister of 10 tablets costs about 65 rubles, respectively, a package of two blisters costs 130 rubles.

For babies under 3 years old, it is better to buy the drug in granules, from which the suspension is prepared, even a baby can drink it. In order to know how much water to pour into the package, a measuring spoon is included. Children over 3-5 years old can be given dragees. The remedy is sold without a prescription, but it is not recommended to use it without consulting a doctor.

In what cases is it applied?

Parents should know exactly when Furazolidone can be used. Full information on this issue is given in the instructions for the drug, but it is better to repeat and remember.

Furazolidone tablets are used for gastrointestinal infections of various nature

Indications for use:

The use of Furazolidone is allowed for children of any age, but with an exact indication of the problem that it must solve.

Furazolidone can be used by children of any age, but only with the permission of a doctor.

Consider when to give medicine in relation to the age of the child:

For infants, the drug helps in the treatment of infected burns and wounds. A sterile bandage is moistened with Furazolidone and applied to the affected area.
For babies after a year, the medicine is given in the form of a suspension for diarrhea and other disorders. Prepare it like this: take 100 ml of warm boiled water and pour it into a bottle with granules. When the drug dissolves, shake the vial and give it to the child, observing the dosage.
For children after 3-5 years, the remedy can be taken in tablets.

Dosage calculations

What you should not do is to resort to the help of medicine yourself. The pediatrician should establish the correct dose and tactics of treatment.

The doctor takes into account all the factors: does the baby have chronic ailments, what kind of pathology is, how severe is it. In addition, when calculating the dose, the weight of the child is taken into account. The general recommendation for a daily dose is 10 mg of the drug per 1 kilogram of body weight. These indicators mean that a preschooler at 6 years old, weighing 20 kg, should take 200 mg of Furazolidone during the day, and for a baby at 6 months, 60-70 mg is enough.

Treatment regimen

Doctors have developed rules for taking medication for children and given recommendations on nutrition for the period of treatment with Furazolidone. Parents should remember them well:

Furazolidone should be taken with plenty of water.

during course treatment, the drug should not be taken for more than 10 days;
multiplicity of reception per day - 4 times;
it is necessary to give Furazolidone after meals, drink plenty of water;
it is necessary to reduce the amount of foods in the child's diet that contain tyramine: smoked meats, canned food (meat and fish), chocolate, kefir, yogurt, cheese, legumes.

A nutritional warning is due to the fact that the active substances of the drug, when interacting with tyramine, provoke negative processes. The child may feel dizzy, his pressure will increase, in some cases such negligence leads to serious consequences. Be sure to monitor the nutrition of the baby in order to prevent such problems.

Contraindications

The minimum indicator of toxicity of Furazolidone is the main argument that allowed pediatricians to prescribe the drug for rotovirus and other infections, even for one-year-old babies. However, this quality does not negate the presence of contraindications in the medicine.

There are a number of contraindications in which doctors prohibit the use of Furazolidone

The drug is not used for:

terminal stage of chronic renal failure;
problems with the central nervous system;
lack of glucose-6-phosphate dehydrogenase;
individual intolerance to nitrofurans.

Side effects

Prescribed in the instructions for Furazolidone and its side effects, there are few of them, but they are, which means they require an attentive attitude on the part of parents. It is necessary to monitor the child, giving him medicine. We list the main negative consequences:

allergy, manifested by itching, rash, swelling and redness;
gastrointestinal upset (vomiting, loss of appetite, nausea);
neuritis (formed with prolonged use).

Consequences of an overdose

It is difficult to overdose the drug when you comply with the dosage established for it, but if information on this matter is in the instructions, then there have been such cases. Complications with an overdose:

An overdose of Furazolidone threatens a number of complications

methemoglobinemia and hemolytic anemia;
destruction of liver cells (hepatitis in an acute toxic form);
violation of the cellular composition of the blood and the functions of the cells themselves;
polyneuritis.

What medicines is the drug incompatible with?

If there is a need to use Furazolidone, parents are required to tell the pediatrician what other drugs the baby is taking at this time.

The information is very important, because Furazolidone is not compatible with some agents. Let's list them:

Ethanol. Communication with this drug provokes acute intoxication, manifested by vomiting, headache, fever, nausea, problems with heart rhythm, difficulty breathing.
Antidepressants and monoamine oxidase inhibitors. If the baby is taking medication with phenylephrine, which narrows blood vessels, the simultaneous use of Furazolidone will cause a sharp increase in pressure.
Antibiotics of the aminoglycoside group are able to enhance the antimicrobial effect of Furazolidone.
Foods and medicines that can alkalize urine. Getting into the body together with Furazolidone, they accelerate the process of drug excretion, reducing its therapeutic effectiveness.

What are the analogues?

Analogues compatible with Furazolidone in structure are not produced. There are remedies similar to it in therapeutic action. Which drug to replace the original appointment, the pediatrician decides, based on the diagnosis and nature of the pathogen.

Smecta is a safe drug for adults and children, which helps to cope with disorders and diseases of the gastrointestinal tract

If antibiotics are not required, the child is given Smektu, with a bacterial infection, the following substitutes are recommended:

Tool name	Release form	Active substance	Indications	Child's age
Enterofuril (more in the article:)	suspension and capsules	nifuroxazide	diarrhea of an infectious nature in acute or chronic form	suspension - from 1 month, capsules from 3 years
Naxojin	tablets	nimorazole	trichomonas infections, giardiasis amoebiasis; vincent's gingivitis	5 years and older
Furadonin	tablets	nitrofurantoin	urinary tract infections of a bacterial nature, prevention of intestinal infections during cystoscopy, catheterization	from the 1st month
Stopdiar	tablets; suspension	nifuroxazide	acute and chronic diarrhea	at 2-4 years capsules, suspension from 2 months
Negro	tablets	nalidixic acid	gastrointestinal infections; pyelonephritis; cystitis; urethritis; prostatitis; cholecystitis.	from 2 years old

Furazolidone is effective against various infections and has a multilevel effect. Pediatricians note its low toxicity, but it also has contraindications and side effects that lead to serious complications. Obviously, with such characteristics, the drug should not be used alone. The decision on its use should be made by a specialist, a doctor who is able to properly build treatment and avoid negative consequences.

Furazolidone is a broad-spectrum drug. The main advantage is that it has an antibacterial effect on pathogenic microflora, which allows you to quickly suppress the manifestation of various infections, fights the unpleasant consequences of poisoning, pest infestation. Parents often keep the drug in the medicine cabinet and give furazolidone for diarrhea to children of different ages.

The medicinal qualities of the drug are that it stimulates the immune system and at the same time destroys a variety of pathogens. The result is achieved by increasing the activity of leukocytes, which absorb and process bacterial cells, and prevent the development of the inflammatory process. The simplest unicellular organisms and pathogenic bacteria die due to respiratory failure and slowing down of metabolic processes, which slow down the growth of microorganisms and their reproduction.

Under the action of the main active ingredient - furazolidone - the destruction of the cell membranes of pests occurs, the activity of microorganisms decreases, they cease to release toxic toxic substances into the blood and intestines.

The main advantage of the drug is that microorganisms slowly develop resistance to it, which allows you to quickly and effectively eliminate the disease and eliminate its symptoms and consequences.

Shigella, Giardia, Salmonella, Trichomonas and other dangerous, harmful microorganisms that cause intoxication of the body die from Furazolidone.

The pharmacy offers this pharmaceutical product in the following dosage forms: powder and tablets. It is rare to find granules for sale.

There is no substitute or analogue having the same composition.

The effectiveness of the use in diarrhea in children

The digestive system of children is in a state of development and has not yet had time to develop important and necessary enzymes for normal functioning. It is poorly protected from the influence of pathogenic microorganisms. Rotavirus, infection, and other pests cause unpleasant symptoms such as diarrhea, abdominal cramps, vomiting, and bouts of nausea. Furazolidone is designed to help with such conditions and quickly improve the patient's well-being.

Use strictly with the permission of the pediatrician. The doctor will calculate the dose and give important recommendations for taking. The medicine has a long list of side effects, contraindications.

Indications for appointment:

food poisoning;
dysentery;
salmonellosis;
paratyphoid, typhoid fever;
inflammation of the mucous membrane of the gastrointestinal tract.

In the cases described, the therapeutic efficacy of the drug is due to its ability to suppress pathogenic intestinal microflora, not a single harmful bacterium will go unnoticed. To speed up recovery, it is necessary to combine treatment with plenty of fluids (pure still water, tea, compote). Liquid and Furazolidone together export dangerous pests from the intestines.

Dosage for children with diarrhea

The official instruction contains information that powder and tablets for diarrhea for children containing furazolidone are allowed to be given from the age of one. In medical practice, the age of patients who are prescribed this antibacterial drug is much higher - 3 years and older.

Dosing is individual for each individual victim. Formula for calculation: 10 mg / 1 kg of body weight. According to this formula, the daily dosage is calculated, the resulting figure must be divided into 3-4 doses.

Example: if a child weighs 20 kg, then the daily dose is 200 mg. From this it turns out that 50 mg of Furazolidone is one dose - 1 tablet of 0.05 g.

The tablet form is allowed to be taken only after the child reaches the age of three.

3-year-old child - ½ tablet, number of doses - 3 times a day.
3 to 12 years - take 1 tablet 3 times a day.
In older age - 1 ½ tablets up to 4 times a day.

Furazolidone is prescribed to children only by the attending physician, the dosage in tablets for diarrhea is calculated individually, depending on the severity of the disease, the characteristics of growth and development, and the presence of chronic diseases.

Therapy lasts a course of no more than 7 days. Improvements in the condition occur 2-3 days after taking the first dose.

If profuse diarrhea continues after 5-7 days, you should contact your doctor to review the treatment regimen.

For young children, the use of Furazolidone suspension is indicated. It is prepared from granules. For dilution, water is used, which is added to the vial up to the indicated mark. The finished solution is stored in the refrigerator until the end of the therapeutic course. Before use, the contents should be shaken well.

Daily dosage of Furazolidone suspension:

0-1 year - the maximum volume reaches 4 ml;
at the age of 1 to 2 years - the dose is increased to 5 ml;
for 2-4 year old children, 6-7 ml of the drug is indicated;
children 5-6 years old are allowed to increase the dose to 7.5-8.5 ml.

The drug in liquid form is approved for use in infants. If a newborn baby falls ill, it is necessary to choose an analogue with a safer action. At one month or older, treatment with a liquid suspension of Furazolidone is possible, but strictly as prescribed by the doctor and under his regular supervision.

Features of the use of Furazolidone to increase therapeutic efficacy:

The tablet, suspension is drunk after a meal. This helps the active substance to be absorbed faster into the digestive organs.
To enhance the effect of an antibacterial drug, it is recommended to drink plenty of water.
By decision of the doctor, it is possible to combine with sorbents for diarrhea caused by poisoning with poisons, toxins, poor-quality food.

The main advantage of the drug is its rapid absorption into the tissues of the digestive tract. The highest concentration of the active substance is observed already in the first half an hour after ingestion and remains in the child's blood for 5-6 hours or longer, depending on the individual characteristics of the organism.

The body does not absorb Furazolidone. The minimum amount of the active substance (only 5%) enters the systemic circulation, but is soon excreted naturally - through the urinary system. After application, after some time, urine staining in a bright yellow or brown color is observed.

In order not to disturb the rate of absorption and the therapeutic effect of the drug, you need to know that it cannot be used simultaneously with antitussive drugs. If the child is being treated with any medicinal substances of internal and external action, be sure to inform the doctor.

Contraindications for use

Prescribe Furazolidone for diarrhea in a child should be used with caution. The agent of antibacterial and immunostimulating action has contraindications for use. The list includes the following diseases and conditions:

lactose deficiency.
High sensitivity to the main component or one of the excipients in the composition.
Chronic or acute renal failure and various pathologies of the kidneys.
Liver diseases.
Violations in the process of production of enzymes.

The instruction indicates that if the dosage is violated or if the drug is taken in a child who has contraindications to it, the following side effects may develop:

cramps in the abdomen;
loss of appetite;
nausea;
angioedema;
vomit;
bitter taste in the mouth;
allergic rash and urticaria.

With the development of at least one of these symptoms, it is necessary to stop treatment and seek the advice of a pediatrician.

Children with an overdose may develop cough, shortness of breath, anemia, fever, fever. This condition can lead to liver poisoning and death.

Be careful when treating diarrhea in young children. Always study the list of contraindications and symptoms of an allergic reaction to the drug!

Just one tablet of Furazolidone is able to stop the frequency and volume of bowel movements. Diarrhea, excruciating pain in the abdomen, constant nausea and bouts of vomiting are not separate symptoms, but signs of disorders in the digestive system. In children, such disorders occur as a result of infection with an intestinal infection. Furazolidone is able to quickly eliminate the symptoms and eliminate the cause of poor health. However, it is impossible to self-medicate without making an accurate diagnosis and doctor's control. This threatens a number of complications and the transition of the disease into a severe form.

Babies are quite sensitive to germs and infections, especially to intestinal, rotoviruses. To help the child's body cope with vomiting, nausea, indigestion, use the drug Furazolidone, recommended for children in tablets for diarrhea.

An unstable immune system is not yet strong enough to actively resist pathogenic microbes that spread in the digestive tract and poison the body with toxins.

Pharmacological properties

Furazolidone for children is an antibacterial and antiprotozoal drug.

Among modern drugs in the treatment of loose stools, it has a number of advantages, because it helps to quickly cope with diarrhea at an affordable price.

Furazolidone for children with diarrhea will be effective if the problem is caused by the following reasons:

Food poisoning.
Dysentery.
Enterocolitis.
Salmonella.

The drug Furazolidone used for diarrhea in children belongs to the group of antimicrobial, antiseptic, potent agents, therefore, despite its effectiveness, you need to know exactly how to take Furazolidone.

This medicine perfectly resists the growth of pathogenic microflora, breaking the bonds of bacteria in the body. But at the same time, the active substances slightly violate the natural flora of the intestine, do not depress the immune system with debilitating diarrhea.

Release form

Due to the fact that this medication has multiple side effects and contraindications, it is recommended to use Furazolidone in tablets for children with diarrhea as prescribed by the therapist. But it is worth noting that analogues that completely coincide in pharmacology and pharmacodynamics are very difficult to find.

For diarrhea in children, Furazolidone is offered for sale in several main forms:

Tablets 50 mg.
Granules for the manufacture of suspensions of 50 or 100 g.

Indications for use

The active ingredient of the drug is a substance consonant with the name of the drug, a derivative of nitrofurans, as well as a number of additional elements that help in the fight against the root cause of loose stools.

Furazolidone for children in tablets for diarrhea will be effective if the problem is caused by the following factors:

Worms, giardiasis.
Rotavirus infection.
Salmonellosis.
Dysentery.
Food poisoning.
Violation of the microflora.
Inflammation of the gastrointestinal mucosa.

The list of indications is quite extensive, but despite the effectiveness of the drug, it should be used only under the supervision and on the recommendation of a doctor.

Dosage for pediatric use

With diarrhea, children in tablets are allowed to take Furazolidone only from the age of 3 and must be drunk strictly following the instructions:

The daily rate of the active substance is 6-7 mg per 1 kg of weight.
One tablet - 0.05 g, based on the weight of the patient, calculate the required amount of the drug.
The dose is divided into 3-4 doses within 24 hours.
Consume after meals with plenty of water.

The dosage of Furazolidone for children in tablets for diarrhea is prescribed in a specific case separately by the attending physician, and based on the weight and age of the baby, the severity of the disease, and the presence of chronic pathologies.

When, after 5-7 days, the condition has not improved, the doctor will definitely prescribe a change in the drug.

If you take a higher dose or a long course of treatment, you are more likely to develop an overdose.

Features of use

In order not to cause complications in the baby, provide the most comfortable conditions for taking the drug.

Furazolidone with diarrhea should be used, following some recommendations of specialists:

It is better to take children with diarrhea (tablets or solution) after meals for good absorption of the active substance.
At the same time, according to the doctor's prescription, you can take antihistamines, as well as complex B vitamins for the prevention of neuritis.
To remove poisons and toxins from the body, it is advised to take sorbents, such as activated charcoal, Smecta, Polysorb, together with the Furazolidone medicine for children.
You should not use cough and cold remedies at the same time as this medication.

Contraindications

Among the conditions in which it is not advisable to take Furazolidone for children from diarrhea, the following are distinguished:

Hypersensitivity to one of the components of the drug.
Renal dysfunction in children in acute or chronic form.
Deficiency of glucose-6-phosphotdehydrogenase.
lactose deficiency.
neurological dysfunction.
Liver diseases.
Diabetes.

Side effects

Adverse consequences after taking Furazolidone with diarrhea in children are possible if you violate the prescriptions of a qualified specialist, the dose, change the course of treatment yourself.

Therapy of an intestinal disorder without consulting a doctor can lead to the following effects:

Decreased appetite.
Abdominal pain.
Bitterness in the mouth.
Vomit.
Nausea.
Urticaria, allergic rash.
Quincke's edema.

In this case, you must stop drinking the drug and seek the advice of a specialist.

Overdose

If it is unreasonable to take Furazolidone for diarrhea in children, change the dosage of the drug, the following complications may occur in babies:

Anemia.
Cough, shortness of breath.
Increased body temperature, fever.
Poisoning of liver tissue.

If the patient intentionally or accidentally received too high a dose of Furazolidone, it can be deadly for children, you should immediately call an ambulance. At the hospital, the baby will undergo an emergency gastric lavage.

How quickly does the medicine work?

The advantage of using the drug is that the active substances are quickly absorbed into the tissues of the digestive tract. The required concentration in the blood of the baby lasts at least 5-6 hours.

Drug Interactions

The drug for diarrhea Furazolidone for children is quite compatible with drugs from the group of antipyretic, antihistamine medicines. But despite this, it is better to consult a doctor about additional treatment.

During the period of therapy, it is necessary to stop taking alcohol-containing drugs. Otherwise, the baby may show redness of the face, dizziness, heaviness in the chest.

Analogues

In some situations, it is impossible for children to take Furazolidone for diarrhea, then it is important to use analogues of the drug.

To date, a drug that replaces Furazolidone for diarrhea for children with a similar active substance has not been developed.

But if the liquid stool in the baby is caused by food poisoning, it is advisable to use the drug "Nifuroxazide". In case of indigestion provoked by intestinal infections, drugs such as Enterofuril, McMiror, Furamag effectively help.

The drug Furazolidone for diarrhea in a child is a well-proven medicine that effectively helps with diarrhea in patients from 3 years of age. The advantage of the drug is the fact that it has a positive effect in children in a short time and at an affordable price.

ponosnevopros.ru

Furazolidone: what are these pills from?

The use of Furazolidone in tablets should be strictly prescribed by a doctor. and under his control, since this medicine belongs to the group of nitrofurans, which, if used irrationally, can harm the human liver and kidneys. When asked why Furazolidone is used, doctors give an exact answer - from any infectious inflammatory diseases of the gastrointestinal tract, genitourinary system, and also the skin.

The active components of the drug can affect trichomonas, salmonella, shigella, gram-negative bacteria, as well as gram-positive flora inside a person. Furazolidone demonstrates weak activity in relation to purulent and anaerobic infections. This is due to the fact that the principle of action of its components is to block monoamine oxidase.

Indications for use

To predetermine what Furazolidone helps from, you need to know the main medical indications for taking such pills. As mentioned earlier, it is a broad-spectrum antimicrobial and antibacterial drug that can fight inflammatory processes and infections of several systems:

typhus, and also paratyphoid;
giardiasis;
dysentery baccilar;
enterocolitis;
trichomonas infection;
loose stools, which are provoked by intestinal poisoning and infection;
urethritis and cystitis;
wounds and burns of the skin with infection.

Instructions for use for adults

In order for Furazolidone to adult patients to help eliminate pathogens and accompany the recovery of a person, it is important to strictly follow the instructions for using the tablet.

The dosage is prescribed exclusively by a medical specialist, who is repelled by the age of the patient and the diagnosis.

In the case of trichomonas colpitis a dose of 100 mg of the drug is prescribed 3-4 times a day, in parallel, the powder is injected into the vagina at a dose of 5-6 mg, and rectal suppositories are also administered at a dose of 4-5 mg. The duration of treatment for such an infection is 1-2 weeks.
With food poisoning, dysentery or paratyphoid 1500 mg of the tablet component is prescribed 4 times a day, this treatment regimen continues for 5-10 days.
For the treatment of Trichomonas urethritis the doctor prescribes a dosage of 100 mg of the substance 4 times a day, the duration of admission is 3 days.
Wound infections and skin burns treated by applying a solution of Furazolidone in the form of wet-drying dressings. In addition, it is necessary to carry out irrigation of the skin.

In order not to provoke the development of side effects, you should not deviate from the indicated norms for taking the drug.

Instructions for use for children

Children need to take Furazolidone by dissolving the tablet in boiled water. To do this, water is poured to the indicated mark, such a solution is taken after a meal, drinking plenty of medicine with water. This will help its components to be absorbed better and faster and begin its active action against pathogenic bacteria and microbes.

Furazolidone should be taken according to the instructions for children three times a day, and the dosage is prescribed by the attending doctor according to the diagnosis:

children under 3 take 0.01 grams active substance for each kilogram of weight, after which this dose is divided into 3-4 doses per day with a uniform time interval between them;
children 3-7 years old take 0.13 grams component of tablets for each kilogram of their weight according to the same principle;
children 7-14 years old treat the disease with the calculation of 0.14 grams per kilogram of body weight, the resulting dose is also divided into 3-4 doses per day.

The indicated dosage of Furazolidone for children is generally accepted, depending on the individual characteristics of the child's body, the doctor can adjust it.

Furazolidone for cystitis

Cystitis is an infectious disease of the bladder, which is most common among women, it is caused by pathogenic bacteria inside the body. The drug Furazolidone has proven to be an effective remedy for curing such a disease. The tablet is taken orally after a meal, drinking plenty of clean water.

For the treatment of cystitis, a dose of 0.1 g of the component (2 tablets) 3-4 times a day will be sufficient, the course of therapy does not exceed 3 days. To fix the result of treatment after pills, a woman is prescribed to use suppositories or powders for topical use. Thus, the full course of treatment will be 10-14 days. The maximum allowable dose per day is 0.8 g, which is equivalent to 16 tablets, a single dose allows no more than 0.2 g or 4 tablets.

Furazolidone for diarrhea

If loose stools in a person are provoked by the action of pathogenic bacteria and infection, then the doctor prescribes a course of treatment with Furazolidone. The therapeutic effect depends only on the dosage indicated by the doctor. If you stick to small doses, the drug has a bacteriostatic effect, in large quantities a bactericidal effect will be obtained.

How to take Furazolidone:

For infants with diarrhea, 0.01 g is prescribed for each kilogram of weight, the resulting dose is divided into 3-4 doses and given out after the same amount of time. Duration of treatment - no more than 10 days.
Children over 1 year old take 10 mg per kilogram of body weight, the resulting amount of the drug is also divided into 3-4 doses.
Children over 5 years of age take 25-50 mg of the drug component, which is equivalent to 0.5-1 tablet according to the same scheme as previously indicated.
Adult patients are prescribed 2-3 tablets of 100-150 mg of the active substance 4 times a day.

The proper effect of the treatment should occur on the 2nd-5th day of taking the tablets. If this does not happen, the doctor prescribes another drug.

Contraindications and side effects

In order not to disrupt the functioning of the internal organs and not aggravate the state of health, before taking Furazolidone, you should carefully study the list of contraindications. It indicates those categories of persons to whom the active components of the drug can cause harm and disrupt the functions of internal organs.

Furazolidone is contraindicated:

people with increased intolerance to one or another component of the remedy;
persons who have kidney and liver diseases;
patients with congenital enzyme deficiency;
children under 1 month old.

If these warnings are not followed, Furazolidone causes a number of side effects:

nausea accompanied by gag reflexes;
loss of appetite;
liquid stool;
headache;
weakness and decreased performance;
dizziness;
drowsiness;
manifestations of allergies in the form of a rash and itching;
changeable mood;
prostration;
liver intoxication.

In order not to cause such phenomena, doctors strongly do not recommend self-medication with such a drug.

Furazolidone: consumer reviews

My two year old son was diagnosed with an intestinal infection. The doctor prescribed Furazolidone, which I prepared in the form of a suspension of granules and gave, strictly following the instructions of the specialist. By the evening, the child felt better, after undergoing a course of treatment, all tests were normal. The main thing is not to self-medicate, since most drugs contain chemistry in their composition.

Anastasia

I am often worried about cystitis, especially in the cold season. When I started to get worse, I went to the doctor. He prescribed me Furazolidone, took pills 4 times a day and so on for 5 days. The next day after starting therapy, I already felt significant relief. One side effect appeared - drowsiness, you want to sleep all day, but for getting rid of cystitis this is a meager price.

Gregory

I have a hard and dangerous job, as a result of negligence, I burned my hand badly. Without going to the emergency room out of stupidity, it turned out that an infection was introduced into the wound. After that, I had to seek medical help. For some time I was bandaged with Furazolidone. The healing process began from the second day of treatment. The affordable price could not but rejoice, I spent mere pennies on the treatment.

Drug analogues

In the event that there are contraindications to taking the drug or the usual intolerance of the components, Furazolidone analogues are prescribed. Such drugs either have a different composition, but have an identical effect on the focus of the disease, or suggest exactly the same composition of the components.

List of analogues:

Befugin in the form of a suspension for diseases of the gastrointestinal tract.
Negram - an antibiotic for urethritis, cholecystitis, pyelonephritis, etc.
Finer is a syrup that treats problem skin and constipation.
Gepar compositum - tablets in case of ailments of the liver or gastrointestinal tract.
Bitol is a suspension that is prescribed in case of infections of the respiratory organs, kidneys, gastrointestinal tract, genital organs, ENT organs, the causative agents of which are strains, salmonella, shigella.
Confizim is a complex for the digestive system.
Norbactin is an antibiotic for infections that have formed as a result of sensitivity to norfloxacin by sensitive microorganisms.
Vis-nol - capsules from ulcers of the duodenum and stomach, in the case of functional dyspepsia, but not against the background of organic diseases of the gastrointestinal tract.

Only the attending physician can prescribe a suitable alternative route for the treatment of an infectious disease.

Expert opinion

According to doctors, Furazolidone is an effective drug for many inflammatory and infectious diseases, despite its low cost - from 80 to 150 rubles. The drug is well tolerated by the body of patients, cases of side effects were very rare. The drug is not prescribed to patients with kidney and liver problems, pregnant women, and newborns.

Infectious diseases are a big threat to health, so doctors insist on visiting a specialist and not self-medicating. The drug is a strong agent against bacteria and microbes, in case of an incorrectly established diagnosis and dosage, it is possible to upset the balance of microflora and aggravate the course of the disease.

samchist.ru

Release form

There are two pharmaceutical forms of Furazolidone.

Tablets. One tablet of the drug contains 50 mg of the main active ingredient. The package contains ten of these tablets.
Granules. Granules intended for the preparation of the solution are packed in a small jar with a volume of 150 ml. The package contains 50 g of active ingredient.
Suspension. Available in a volume of 50 ml.

All three forms are used to treat children. However, granules and suspension are not sold in Russia. The granules are produced in Poland, Peru, Colombia and Venezuela. The suspension is produced in Peru and Vietnam. Therefore, for these dosage forms, you need to go to these countries or order medicine from there.

When applied

dysentery infection;
food poisoning and toxic infections;
typhus, paratyphoid diseases.

The drug is also used in the complex treatment of rotavirus infection. In this case, it inhibits the growth of pathogenic flora in the intestine and contributes to a faster recovery of the intestinal wall after an illness.

According to the official instructions, Furazolidone tablets can be given to a child from the age of one. However, in practice, the drug is prescribed only for older children who can already swallow the pills. In most cases, these are patients older than three years.

The dosage of "Furazolidone" for children with intestinal infections is determined at the rate of 10 mg of the drug per kilogram of weight. This amount of medicine is intended for daily intake. The resulting daily dosage is divided into three to four doses and given to the patient. That is, if the weight of a child, for example, is 20 kg, then he needs 200 mg of the drug per day. It is better to divide this amount into four doses, so you get 50 mg at a time.

Similarly, "Furazolidone" is calculated for a child with giardiasis. But in this case, the daily dosage is 10 mg per kilogram of the child's weight.

Use of granules

If you managed to get the medicine in this form of release, before using the drug, it is necessary to prepare a medicinal suspension from the granules in the vial. To do this, boil and cool the water, which is then added to the bottle with the powder to a special mark. The latter corresponds to a volume of 100 ml. The finished suspension is best stored in the refrigerator during the entire treatment period. Shake the vial before giving it to the patient.

It is better to give the medicine before meals, after taking it, you need to give a sufficient amount of liquid, at least 100-200 ml. The recommended daily dosages of the solution by age are given in the table.

According to the instructions, the liquid form of the drug can be given even to infants. However, the Furazolidone suspension is not used to treat newborns. This is due to the fact that they have an immaturity of the enzymatic system of the liver, and therefore there is a risk of disturbances in the hematopoietic system. Therefore, how much and how to give "Furazolidone" to an infant, you must definitely check with the doctor.

The duration of treatment is usually determined by the doctor. Giving "Furazolidone" to children under one year old and older should be no more than seven to ten days.

Side effects

In most cases, the drug is well tolerated by children. But, according to pediatricians, the following side effects can sometimes occur:

loss of appetite;
nausea;
vomit;
allergies of varying severity.

Contraindications

Contraindications to the use of nitrofurans are the following conditions:

high sensitivity to the components in the composition;
dysfunction of the kidneys, liver;
deficiency of the enzyme glucose-6-phosphate dehydrogenase.

For adult patients, the limitation is pregnancy and lactation. Since the drug has some metabolic features, it is also better to stop taking tyramine-containing products during treatment:

hard cheese;
legumes;
smoked meats.

This is necessary to prevent side effects of the drug.

Compatibility with other tools

The drug is compatible with most pharmacological agents. It can be combined with drugs that improve the functioning of the gastrointestinal tract, antibiotics. So, aminoglycosides and tetracyclines are able to potentiate the action of nitrofurans. The simultaneous use of this medicine with the following drugs is not recommended:

monoamine oxidase inhibitors;
"Chloramphenicol";
"Ristomycin".

It is strictly forbidden to give nitrofurans together with medicines containing alcohol. This can provoke a disulfiram-like reaction, which is manifested by the following symptoms:

vomiting, severe nausea;
increased heart rate;
feeling of lack of air;
cough;
skin redness;
psychomotor agitation.

Therefore, if any medications have already been prescribed to the child, they should definitely be reported to the attending physician.

Where to buy and analogues

"Furazolidone" can be bought at any pharmacy without a doctor's prescription. The price of a medicine in August 2017 is quite affordable: buying a pack of ten tablets costs 80-115 rubles. The cost of the medicine depends on the manufacturer and the trade margin in a particular distribution network.

There are no exact analogues of Furazolidone. However, in pharmacies you can find drugs from the nitrofuran group, which act like Furazolidone:

"Nifuroxazide";
"Enterofuril";
"Nitrofurantoin";
Furazidin.

These drugs have a chemical structure similar to Furazolidone, however, they differ in their action. So, "Nifuroxazide" and its analogue "Enterofuril" are used to treat intestinal infections, since they are practically not absorbed from the gastrointestinal tract. Also in the pharmacy network there is the drug "Dependal M" with metronidazole. The medicine has a convenient children's pharmaceutical form in the form of a syrup.

"Nirofurantoin" and "Furazidin" penetrate well into the systemic circulation, their main point of application is the urinary tract. Therefore, they are often used in the suppressive therapy of chronic infections of the kidneys, ureters and bladder. They are prescribed for cystitis, pyelonephritis, urethritis. "Furazidin" can also be applied topically to wash wounds and treat inflammation on the skin.

The benefits of Furozalidon for children

"Furazolidone" is an inexpensive and effective remedy for intestinal infections. The drug has a number of advantages over other antibacterial agents, including antibiotics:

has its effect only in the intestinal lumen;
effective against various intestinal infections;
contributes to the restoration of the intestinal wall;
does not have a damaging effect on the natural microflora;
practically does not interact with other drugs;
has a low cost.

Children are very difficult to keep track of, so they often have intestinal infections. As a rule, the baby begins an upset gastrointestinal tract, causing vomiting and nausea. As a result, when vomiting, the baby loses a lot of fluid, and dehydration can greatly harm the child, so you need to put Furazolidone in the first aid kit in a timely manner, and if necessary, immediately take action, knowing how to give it to children.

What is Furazolidone

- an antibacterial agent aimed at the destruction of microorganisms that lead to an upset of the gastrointestinal tract. This medication is considered a medicine with a wide spectrum of effects, so doctors widely use it in medical practice.

Each mother cares about the health of her baby, worries that the drug used does not affect the child's body in a negative way, there are no side effects and complicating circumstances, so we will consider all the features of this medicine.

More about Furazolidone

- a medical preparation of synthetic origin, antibacterial effects. It belongs to the group of nitrofurans, which prevent the development of microorganisms harmful to humans. This tool has the main active ingredient - furazolidone. Its amount in the 1st tablet is 50 mg. In addition, each tablet capsule contains excipients: potato starch, silicon dioxide, lactose monohydrate, calcium stearate.

Based on the original instructions for use for children, it is known that this medication is available in the following forms:

Tableted- 10 tablets of 50 mg.
granular. It is used for dissolution in boiled water, for the purpose of use in the form of a suspension.
powder. For children it is used in rare cases. More often required for the treatment of animals.

It can be used for the treatment of children in both tablet and granular form. By themselves, these medicines are identical, but granules are more often used for children who cannot yet drink tablets (under 1 year) or if they are not able to swallow a pill. When buying granulated Furazolidone, a measuring cup is included so that mom cannot make a mistake with the dosage.

"Furazolidone" instructions for use for children (in tablets or granules) states that before buying, you should definitely consult a doctor, because the drug is sold freely, and if the mother has an incorrect diagnosis, the drug can cause undesirable consequences.

The effect of "Furazolidone" on microorganisms

The instruction for children describes the effect of the drug in medical terminology, which puzzles the mother. Let's decipher the principle of action of this medicine:

Influencing the microorganism, "Furazolidone" destroys cell membranes, which leads to blocking of the biochemical processes of the bacterium. As a result, they are not able to multiply or die, it depends on the amount of the dose taken. Therefore, if the child has taken more "Furazolidone", then the microorganisms have no chance of survival, and if the dosage is insufficient, the bacteria are not able to absorb the entire body of the baby.

If we compare antibiotics and Furazolidone, then the former will be more effective, but they depress the child's body, as a result of which the immune system decreases, and this medicine stimulates the immune system to fight the pathogen. Also, "Furazolidone" does not provoke the rapid addiction of bacteria to the main substance, but increases the ability of leukocytes to suppress and dissolve microorganisms in themselves.

"Furazolidone" for children prevents toxic poisoning caused by protozoa and bacteria with their excreted substances. From this, the symptoms caused by intoxication of the body quickly disappear. Also, the drug reduces the effectiveness of the enzyme that is responsible for the breakdown of adrenaline, so during use, the baby may be a little excited.

It should be noted that the absorption of "Furazolidone" occurs through the gastrointestinal tract, and excretion from the body - by the kidneys. Consequently, the urine during taking the tablets acquires a brownish tint.

"Furazolidone" for children: dosage

This medication is prescribed in many cases, consider the most common:

With food poisoning.
Intestinal diseases of infectious origin, in the form of diarrhea, dysentery, typhoid.
Helminth infestations:, giardiasis.
Foci of infection in the urinary and reproductive systems - cystitis, urethritis.
Skin damage (chemical and mechanical). Then, it is customary to dissolve the tablets, treat bandages for dressings and burns.

With symptoms corresponding to infections in the intestines and characterized by pain in the abdominal cavity, nausea with vomiting, you should definitely call a doctor at home. with such symptoms, there can be not only poisoning, but also other diseases in the form of a concussion, appendicitis, etc.

Contraindications for use

In some cases, Furazolidone is categorically contraindicated in the following cases:

If the child has an intolerance to 1 or more of the substances contained in the tablets.
Severe kidney failure.
Forbidden for children under one year old. However, in emergency cases, doctors prescribe "Furazolidone" to the child even at that age. You should not independently assign the severity of the disease to the baby, so as not to get the opposite effect.

Relative contraindications

Insufficiency and kidney disease, expressed in mild form.
Deviations in the functionality of the central nervous system.
Hepatic pathological processes.
Lactose intolerance (the tablets contain milk sugar).
Deficiency of glucose-6-phosphate dehydrogenase.

"Furazolidone" for children: instructions for use

Treatment with "Furazolidone" is extremely necessary to coordinate with the attending physician, because the weight of the child, concomitant diseases, age can play a cruel joke.

In medicine, there is an average normalized dosage - 10 mg per kg. body mass, which is usually divided into 4 doses in order to avoid overdose. The maximum course of therapy with this medication is 10 days.

In order for the product to be well absorbed in the body, it should not be chewed. That is, when using whole granules or tablets, they should be swallowed unchanged, allowing them to split themselves in the stomach. "Furazolidone" should be washed down with plenty of water for better absorption of the gastrointestinal tract.

If "Furazolidone" is prescribed for preventive purposes, then the treatment course will be protracted. Then, for the general maintenance of the child's body, vitamins of group B are additionally prescribed.

The drug can cause side reactions. In order to avoid discomfort (during the reception), you should give up everyday food and go on a diet. To do this, the following must be excluded from the nutritious diet: cheeses, smoked foods, chocolate, sweet, fatty, spices, etc. However, diuretic cranberry or lingonberry decoctions will come in handy.

Overdose

Sometimes, the use of the drug can carry negative consequences. This is caused by a very large amount of medication used.

Such actions are accompanied by the following symptoms:

Hepatic inflammation, in the form of toxic hepatitis.
Breathless.
Heartbreaking cough.
Irritation of nerve endings caused by toxins.
hemolytic anemia.

In case of an overdose, you should immediately stop using the drug and take the following measures:

Rinse the stomach.
Drink a laxative.
Sorbents.
B vitamins.
Antihistamines.

You should also consult a doctor to prevent complications. The specialist is obliged to carry out infusion therapy, and in case of severe poisoning, to clean the blood.

Adverse reactions

Sometimes adverse reactions still accompany the use of the drug, but you should not refuse to use it and reject the suggestion of the attending physician. "Furazolidone" is low-toxic and practically harmless, but the manifestation of side effects is caused, starting from the individual characteristics of the organism.

"Furazolidone" causes the following effects:

Vomiting with nausea.
Refusal of food. If you do not take action, then up to the anorexic state.
Allergies of varying severity.
Pain in the abdominal cavity.

"Furazolidone" is one of the old and proven drugs over the years. It was given by many mothers to help their children, so do not be afraid to use it. Negative consequences, as such, arise due to incorrect dosage selection, refusal to use antihistamines, B vitamins. It is also important to control that the child drinks a lot when taking pills. This will reduce the risk of side effects.

Antibacterial drug, a derivative of nitrofuran

Active substance

Furazolidone (furazolidone)

Release form, composition and packaging

◊ Tablets yellow or greenish-yellow, flat-cylindrical, with a chamfer.

Excipients: potato starch - 20 mg, calcium stearate (calcium stearate) - 1 mg, sugar (sucrose) - 10 mg, tween-80 (polysorbate) - 0.2 mg, lactose (milk sugar) - 18.8 mg.

10 pieces. - non-cell packing contour.
10 pieces. - blister packs (2) - cardboard packs.
10 pieces. - blister packs (3) - cardboard packs.
10 pieces. - blister packs (4) - cardboard packs.
10 pieces. - blister packs (5) - cardboard packs.
50 pcs. - polymer cans (1) - packs of cardboard.

pharmachologic effect

Means, derivative of nitrofurans. Active against gram-positive and gram-negative microbes, Trichomonas spp., Giardia lamblia. The most sensitive to furazolidone are Shigella dysenteria spp., Shigella flexneri spp., Shigella boydii spp., Shigella sonnei spp., Salmonella typhi, Salmonella paratyphi.

Weakly affects pathogens of purulent and anaerobic infections. Microbial resistance develops slowly. Blocks monoamine oxidase. Nitrofurans disrupt the processes of cellular respiration of microorganisms, suppress the tricarboxylic acid cycle (Krebs cycle), and also inhibit the biosynthesis of nucleic acids of microorganisms, resulting in the destruction of their shell or cytoplasmic membrane. As a result of the action of nitrofurans, microorganisms release less toxins, and therefore an improvement in the general condition of the patient is possible even before a pronounced suppression of the growth of microflora. Unlike many other antimicrobial drugs, they not only do not inhibit, but even activate the body's immune system (increase the complement titer and the ability of leukocytes to phagocytize microorganisms).

Pharmacokinetics

Well absorbed when administered orally. Against the background of inflammation of the meninges in the cerebrospinal fluid, concentrations equal to those in . It is rapidly and intensively metabolized mainly in the liver with the formation of a pharmacologically inactive metabolite (amino derivative). It is excreted mainly by the kidneys (65%), small amounts are found in the feces, where therapeutic concentrations are achieved against pathogens of intestinal infections.

Indications

dysentery;
paratyphoid;
giardiasis;
food poisoning.

Contraindications

pregnancy, lactation;
increased individual sensitivity to the group of nitrofurans;
terminal stage of chronic renal failure;
deficiency of glucose-6-phosphate dehydrogenase;
children's age up to 3 years (for this dosage form).

Carefully

Chronic renal failure, deficiency of glucose-6-phosphate dehydrogenase, diseases of the liver and nervous system.

Dosage

Inside, after eating.

At dysentery, paratyphoid and food poisoning- 100-150 mg 4 times / day (but not more than 800 mg), for 5-10 days.

With giardiasis: adults- 100 mg 4 times / day, children- 10 mg / kg / day, distributing the daily dose into 3-4 doses.

The highest single dose for adults is 200 mg; daily - 800 mg.

Side effects

Decreased appetite, up to anorexia; nausea, vomiting; allergic reactions (skin rash, flushing and itching of the skin, angioedema).

With prolonged use - neuritis.

Overdose

Symptoms: acute toxic hepatitis, hematotoxicity, neurotoxicity (polyneuritis).

Treatment: drug withdrawal, large fluid intake, symptomatic therapy, antihistamine drugs, group B.

drug interaction

Furazolidone in combination with ethanol can lead to the development of disulfiram-like reactions, and therefore their simultaneous administration is not recommended. Antidepressants, monoamine oxidase inhibitors, amphetamine, phenylephrine, tyramine can cause a sharp increase in blood pressure.

special instructions

Increases sensitivity to the action of ethanol.

Medicines that alkalinize urine reduce the effect, while acidifiers increase it.

Aminoglycosides and enhance antimicrobial properties.