Rules for taking Indapamide for high blood pressure. All about Indapamide tablets When to take indapamide retard in the morning or evening

Indapamide is a popular drug for the treatment of hypertension. This is a diuretic, moderate in strength, long-lasting in its effect.

It has a vasodilating effect and reduces their total peripheral resistance. One of the valuable qualities of Indapamide is its ability to reduce hypertrophy of the left ventricle of the heart.

The drug does not affect the patient's carbohydrate and lipid metabolism (patients with diabetes are no exception). As for the antihypertensive effect, with regular use of the medicine it appears by the end of the first/beginning of the second week.

Throughout the day, this effect is observed to persist with a single dose of the tablet. Patients with hypertension are often interested in the question of how and when to take Indapamide so that it shows all its best qualities. And this is correct, since compliance with the instructions is an urgent necessity for the rapid restoration of health.

1 Dosage
2 When is the best time to take it?
3 Indapamide for blood pressure
4 For diabetes
5 Pregnancy and lactation
6 Adverse reactions
7 Special instructions
8 Videos on the topic

Dosage

The drug is prescribed one tablet per day. Its weight is 2.5 mg, the medicine should be taken in the morning. The control period is 4-8 weeks, during which time the therapeutic effect should appear.

Indapamide tablets

Sometimes it is not observed, but the dose should not be increased. When the norm increases, there is a risk of side effects. However, there is always a way out - doctors will prescribe another antihypertensive drug that is not a diuretic.

When using Indapamide, you must follow the instructions to avoid side effects.

There are cases when treatment begins with taking two drugs at once. The dose of Indapamide still remains the same - one tablet per day in the morning.

When is the best time to take it?

The tablets are taken without chewing. Reception time is morning.

The drug is washed down with a sufficient amount of ordinary boiled water.

As a rule, use one glass of liquid. The use of this medicine does not depend on food intake.

Correct use of the drug is the key to its effective action.

Indapamide for blood pressure

The medicine is becoming increasingly popular because it has significant advantages over its analogues. These include:

stable decrease in pressure;
drug safety;
no restrictions (indicated for the elderly, diabetics, patients with gout).

A valuable quality of the medicine is that it does not have a negative effect on metabolism. As a result of its use, the level of blood sugar and uric acid remains the same.

All of the above does not mean at all that Indapamide can be used uncontrollably or taken without a doctor’s recommendation. If we are talking about a hypertensive crisis, this medicine should not be used. It is not suitable for quick help. The drug begins to act only after long-term use. Duration – one to two weeks of constant use, while the pressure decreases smoothly.

Sometimes Indapamide is called the "grandfather's remedy." Now there are many fast-acting tablets that can greatly reduce blood pressure in a short time. But such drugs have a large number of side effects. Therefore, many patients choose the completely harmless Indapamide for treatment.

In order for the tablets to show their full potential, it is prescribed in combination with other drugs. The goal of treatment is to maintain stable blood pressure (below 135-140/90 mmHg).

To achieve maximum results, doctors prescribe Indapamide in combination with other non-diuretic drugs.

Numerous studies conducted since the 1980s have shown that the drug reduces the risk of complications for hypertensive patients. We are primarily talking about such serious diseases as stroke and heart attack.

The only inconvenience when taking Indapamide is the combination with several drugs. But modern pharmacology has done everything for the benefit of patients. Several active ingredients began to be included in one medicine.

Combined blood pressure drug Co-Perineva

Thus, Noliprel and Co-Perineva are products that include Indapamide with Perindopril. Ko-Dalneva already consists of three active ingredients. It includes Indapamide, Amlodipine, Perindopril. If your blood pressure is 160/100 mmHg. and above, it is worth discussing with your doctor the possibility of taking combined medications.

Indapamide is an excellent medicine intended for long-term use; it is not possible to relieve a hypertensive crisis with its help.

For diabetes

The drug is often prescribed to diabetics when their blood pressure rises. Take the medicine in combination with other tablets.

Many diuretics increase blood sugar levels, which is not the case with Indapamide.

Such cases while taking this medicine are rare. But the patient is still recommended to use the glucometer more often to measure glucose levels. Indapamide is used in combination with other drugs.

Indapamide is an effective and harmless drug for lowering blood pressure in patients with diabetes.

ACE inhibitors and angiotensin II receptor blockers lower blood pressure and protect the kidneys from complications. Patients with diabetes are prescribed Indapamide and Perindopril, which are classified as ACE inhibitors. This combination lowers blood pressure and reduces the risk of cardiovascular complications.

As a result of the action of the drugs, the amount of protein in the urine remains stable and the kidneys do not suffer from complications of diabetes.

Noliprel, containing indapamide with perindopril, is in particular demand among patients.

Their goal is to lower blood pressure and maintain it at 135/90 mmHg. Art. When Noliprel does not allow it to be achieved, Amlodipine is added to the medication regimen.

Pregnancy and lactation

Indapamide is a diuretic. When a pregnant woman experiences hypertension or edema, the question arises: is it possible to take this drug?

Doctors answer unequivocally - taking Indapamide during pregnancy is completely unjustified.

The medicine can cause insufficiency of fetal-placental blood flow, and this, in turn, can provoke the development of fetal malnutrition.

If during lactation the mother suffers from hypertension and it is no longer possible to do without medications, doctors may prescribe this drug. In this case, breastfeeding is stopped immediately to avoid intoxication of the baby’s body.

Pregnancy and lactation are not the best times to take Indapamide; in the first case it is prohibited, in the second it leads to stopping feeding the child.

Adverse reactions

Indapamide is a valuable medicine. Its use is rarely accompanied by side effects; they were recorded in only 2.5% of patients. Most often this is a violation of electrolyte metabolism.

Side effects include:

headache;
weakness;
dizziness;
Quincke's edema;
body aches;
nausea, vomiting;
constipation;
arrhythmia, arterial hypotension;
cough;
various allergic manifestations (purpura, urticaria, photodermatosis).

Despite the long list of side effects, among which one can see such a formidable manifestation as Quincke's edema, the drug Indapamide causes negative conditions extremely rarely.

Use of the medicine (very rarely) may affect laboratory tests, for example, increase the level of creatinine, urea, in the blood.

special instructions

Often, after stabilizing the pressure and feeling well, patients stop using medications.

This is a wrong decision; doctors advise taking Indapamide constantly.

Reducing the dosage or completely stopping the medication should only be done under the supervision of a physician.

An important step is regular blood tests for creatinine, potassium, and other indicators that will interest the doctor.

In the first week of taking Indapamide, you should avoid working with dangerous machinery or driving a car. When you are sure that the medicine does not have negative effects, return to your previous lifestyle. The drug can be used regularly for six to nine months, after which you can consult your doctor for recommendations.

Video on the topic

How to take Indapamide for high blood pressure:

Indapamide is a medicine for long-term use; laboratory tests will determine the time of administration.

The information on the website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.

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The diuretic drug Indapamide can effectively lower blood pressure. In this case, normalization occurs gently, and the diuretic effect is minimal. The drug has accumulative properties. The maximum result is observed 8-10 weeks after the start of use. The medication has a list of contraindications and side effects. To prevent the latter, you should consult a doctor and carefully monitor your health.

Composition, properties and release form

Indapamide tablets belong to the group of diuretics and antihypertensive drugs. The main actions include a gradual decrease in pressure. At the same time, the diuretic effect can be controlled, which helps prevent dehydration and maintains the balance of substances normal.

Externally, the tablets are white or slightly grayish in color, round, coated. The action of Indapamide Retard is due to the presence of the active substance indapamide. Pills contain 2.5 mg of the drug. The tablets also contain:

Enter your pressure

Mechanism of action

The medicine effectively lowers blood pressure.

The effect of Indapamide on the body is based on the increased removal of sodium and chlorine elements from the blood. At the same time, the drug has practically no effect on the concentration of potassium and magnesium. As a result, blood pressure decreases and a mild diuretic effect is observed. The value of reduced pressure does not depend on the amount of medication taken. As the dose increases, the volume of fluid released changes. The medicine is characterized by a cumulative effect. If you constantly take Indapamide for 8-12 weeks, you will achieve the maximum result from treatment.

Why is Indapamide prescribed?

Indications for use describe situations in which the use of the product brings maximum benefit and results. A diuretic drug is widely used for high blood pressure. Indapamide is prescribed as an independent remedy or as an addition to complex therapy. If the patient does not have hypertension, taking pills causes a deterioration in the condition and adverse reactions.

Instructions for use and dosage

During treatment, it is recommended to adhere to the doctor's instructions according to the instructions.

You should take diuretics strictly according to the schedule specified by your doctor. Indapamide can be taken before or after meals. For high blood pressure, 1 tablet in the morning is recommended. The medicine is not taken in the evening, since Indapamide is a diuretic medication. If necessary, you can take the pill with a small amount of liquid. The result begins to appear no earlier than 2-3 weeks from the start of therapy. This is due to the cumulative effect. If the duration of use exceeds 4-5 weeks, but there is no effect, the drug should be discontinued or the daily dosage revised.

Use during pregnancy and lactation

"Indapamide" for blood pressure should be taken according to your doctor's recommendations. All risk factors should be taken into account. These include the period of gestation. Taking the drug in this case is dangerous. "Indapamide" during pregnancy has the ability to penetrate through the placenta to the fetus. At the same time, the diuretic reduces blood pressure and provokes oxygen starvation. Instructions for use prohibit the use of a diuretic during breastfeeding. "Indapamide" is harmful to infants as it passes into mother's milk. If a woman needs to take the drug, then during therapy, feeding is replaced with artificial feeding.

Is it used for children?

The drug is not recommended for children; there is a risk of low blood pressure.

The use of Indapamide for a child with illness is not recommended. It is prohibited to use due to the lack of experimentally confirmed evidence of the safety of the product. Use may provoke cases of low blood pressure in young patients. If you get sick, it is better to resort to alternative drugs. There is an option to use the product every other day with a minimum daily dose and for high blood pressure.

Contraindications

Idapamide should be taken with caution at the beginning of treatment. This is due to the presence of a list of prohibited diseases. The consequence of ignoring the list is obvious side effects. Over time, they develop into health complications. Do not use if you have low blood pressure or gout. Other contraindications to taking Indapamide Tab include:

negative reactions to the composition;
age under 18 years;
taking incompatible drugs;
circulatory disorders in the brain;
urinary disorders;
renal failure;
low level of potassium in the body.

How to understand that there is an overdose?

An overdose of the drug can cause weakness in the body, drowsiness and disturbances in the gastrointestinal tract.

Taking the medicine for a long time without the supervision of a doctor or in violation of the prescribed dosage can lead to an overdose. Long-term use with disturbances is characterized by nausea, hypotension, weakness, drowsiness and disturbances in the functioning of the stomach. At the same time, the balance of substances in the body is quickly disturbed. If you stop and start using the drug correctly, taking into account the prescribed dosage, you can avoid dangerous consequences. The concentration of indapamide in the blood can be reduced by rinsing. Activated carbon or other sorbents act similarly.

Side effects

With prolonged use without interruption, Indapamide begins to have a negative effect on the patient. To prevent adverse reactions, the patient is treated by a doctor. At the same time, it is important to monitor the condition and monitor your well-being. Commonly observed side effects:

allergies in the form of itching, red spots on the body and hives;
dry cough with a burning sensation in the throat;
clouding of consciousness and dizziness;
sense of anxiety;
arrhythmia and palpitations at rest;
dry mouth and lack of appetite;
changes in blood counts.

Indapamide has a mild blood pressure-lowering effect; if you follow the rules for taking it, it rarely causes side effects. The drug belongs to the diuretic drugs.

In the course of complex treatment of hypertension, the doctor must prescribe diuretics, since with the removal of fluid from the body, blood pressure (blood pressure) decreases faster. The pharmaceutical industry has created a lot. Most often, if there is swelling, the doctor prescribes Indapamide for blood pressure. However, the medicine has contraindications and features of use, so treatment should be agreed with a doctor.

The drug belongs to the long-acting thiazide-like diuretics and has a mild lowering effect on blood pressure levels. Indapamide is used for arterial hypertension, when the pressure begins to exceed 140/90 mmHg. Art., and chronic heart failure, especially if the patient has swelling.

The drug is available in the form of tablets and capsules of 1.5 and 2.5 mg. They are produced in Russia, Yugoslavia, Canada, Macedonia, Israel, Ukraine, China and Germany. The active ingredient of the drug is Indapamide.

Indapamide is a calcium-sparing drug, which is good for hypertensive patients with osteoporosis. It can be used by people on hemodialysis, diabetics, and hyperlipidemia. In difficult cases, it is necessary to monitor the level of glucose, potassium, and other indicators recommended by the doctor.

Indapamide for hypertension

Capsules or tablets for blood pressure for hypertension begin to act 30 minutes after consumption. The hypotonic effect lasts 23–24 hours.

The decrease in blood pressure is caused by a hypotensive, diuretic and vasodilating effect - the pressure level begins to fall due to the influence of the active substance, the removal of excess fluid from the body and the dilation of blood vessels throughout the body.

Indapamide also has a cardioprotective property - it protects myocardial cells. After treatment, the condition of the left cardiac ventricle significantly improves in a hypertensive patient. The drug also gently reduces resistance in peripheral vessels and arterioles. Since it moderately increases the rate of urine formation, with which excess fluid is eliminated, it is appropriate to take the medicine if there is edema.

How to take Indapamide for hypertension

For high blood pressure (more than 140/100 mm Hg), the dosage and duration of therapy is selected by the doctor individually. Usually you need to take Indapamide once a day: 1 tablet in the morning. It is allowed to drink on an empty stomach or after a meal - food does not affect the effect of the drug.

Mandatory admission rules:

consume at a clearly established time to maintain a 24-hour interval;
swallow tablets or capsules whole;
drink with still water in a volume of at least 150 ml;
Only on the recommendation of a doctor change the dosage or stop the course of treatment.

The prolonged effect of Indapamide is associated with the gradual dissolution of the drug. If the tablets or capsules are crushed before use, a large amount of the active substance will immediately enter the tissues, causing the blood pressure to drop sharply. A sudden drop in blood pressure disrupts the functioning of all body systems, which is fraught with dangerous consequences.

The following drugs are allowed to be taken with Indapamide:

and other B-blockers;
Lorista (antagonizes angiotensin receptors);
(for heart failure);
Lisinopril (ACE inhibitor);
other medications prescribed by the doctor.

Naturally, only a doctor should select any combination of drugs, since when combining them independently, the compatibility of the active ingredients is often not taken into account. This may result in treatment failure or drug poisoning, which in each case is life-threatening.

Interaction with other drugs

A person is often forced to take several drugs belonging to different drug groups. Their active substances may reduce or enhance the effectiveness of Indapamide. It is worth taking a closer look at how such “interactions” manifest themselves.

The hypotensive effect of the drug increases when used together with antidepressants and antipsychotics - this can cause a sharp drop in blood pressure.

When combined with Erythromycin, a person experiences tachycardia, while in combination with Cyclosporine, the level of creatinine increases. Simultaneous use with drugs that contain iodine can cause dehydration. Potassium loss is promoted by laxatives, saluretics and cardiac glycosides.

It should be borne in mind that corticosteroids and NSAIDs (non-steroidal anti-inflammatory drugs) reduce the hypotensive effect of Indapamide - this reduces the effectiveness of the drug. To avoid such interactions with other medications, the doctor needs to provide a list of all medications and herbal medicines used.

Contraindications Indapamide

Hypertensive patients with concomitant diseases of the urinary, endocrine, digestive and cardiovascular systems should additionally consult a doctor. In some pathologies, this medicine has specific uses or is completely contraindicated.

Indapamide should not be used by children under 18 years of age or by pregnant women. If the drug is prescribed to a woman during lactation, then during treatment the baby is transferred to artificial nutrition.

The use of Indapamide is contraindicated if the following conditions are diagnosed:

individual intolerance;
renal failure;
galactosemia, lactose intolerance;
hepatic encephalopathy;
circulatory disorders in the brain;
hypokalemia;
gout;
anuria.

Before purchasing the drug, it is recommended to study the manufacturer’s official instructions (included in the packaging of the medication), since it displays complete information about the composition, features of use, contraindications, and other data.

Side effects of Indapamide

When used correctly, in 97% of cases the medicine does not have a negative effect on the body. In people belonging to the remaining 3%, Indapamide causes side effects. The most common effect is an imbalance of water and electrolytes: decreased potassium and/or sodium levels. This leads to dehydration (fluid deficiency) in the body. Very rarely, the medicine can cause arrhythmia, hemolytic anemia, sinusitis and pharyngitis.

Other side effects of Indapamide:

allergies (urticaria, anaphylaxis, angioedema, dermatosis, rash);
Lyell's syndrome;
dryness of the oral mucosa;
Stevens-Johnson syndrome;
cough;
weakness;
dizziness;
nausea, vomiting;
muscle pain;
migraine;
nervousness;
liver dysfunction;
pancreatitis;
constipation;
orthostatic hypotension.

Sometimes Indapamide changes the composition of the blood and urine. Tests may reveal a deficiency of potassium, sodium, increased amounts of calcium, glucose, creatinine and urea. Thrombocytopenia, leukopenia, anemia, and agranulocytosis occur less frequently.

What can replace the drug?

Instead of Indapamide, it is allowed to use Indap. This medicine has the same composition, but is produced by a different manufacturer and may have a different dosage of the active substance. If there is a difference, the attending physician should adjust the drug intake.

The doctor will also help you choose analogues with a similar active substance or effect. During an individual consultation, the doctor will tell you which medicine is best to use: Indapamide or Hypothiazide, Arifon Retard, Veroshpiron, Hydrochlorothiazide, Diuver, Acripamide, Ionic, Retapres. It is possible to prescribe other diuretics aimed at lowering blood pressure.

Conclusion

The medicine Indapamide gently reduces blood pressure throughout the day. With its regular and correct use, blood pressure decreases within 7 days from the start of use. But you cannot interrupt therapy at this stage, since the treatment reaches its maximum result after 2.5–3 months. For better effectiveness of the drug, you also need to adhere to medical recommendations: follow a diet for hypertension, adjust the duration of rest, and other prescriptions.

The drug "Indapamide" acts on the vascular walls, relaxing them and normalizing muscle elasticity. Thanks to this drug, the arterioles enlarge, which leads to the unhindered movement of blood in the body. Indapamide tablets - This is a vasodilator, similar in pharmacodynamics to a thiazide diuretic. During the day, the amount of urine produced increases slightly. Together with it, the predominant ions of sodium, chlorine, and potassium are removed from the body. While taking the medicine, carbohydrate and fat metabolism remain normal, which makes it possible for patients suffering from obesity or diabetes to take the drug. When severe, the drug "Indapamide" noticeably reduces the level of hypertrophy. With regular use of the drug, the effect is achieved after 2 weeks, and after 10 weeks the maximum beneficial effect is observed. A single dose of the drug "Indapamide" retains its therapeutic properties for up to 24 hours.

Pharmacokinetics

The blood pressure drug Indapamide is quickly absorbed from the gastrointestinal tract and is excreted from the body mainly in the urine. The content of inactive metabolites in feces is about 20%. The diuretic interacts with plasma and red blood cells and passes into breast milk. With regular use of the drug, no accumulation was observed. Patients with liver failure should use this medicine with caution to avoid the formation of

Indications for use

What does the medicine "Indapamide" help with? Indications for its use are:

Arterial hypertension.
(sodium and water retention in the body).

Contraindications

The use of the drug is limited for the following diseases:

Liver dysfunction.
Renal dysfunction.
Intolerance to the components of the drug.
Hypokalemia.
Poor circulation in the brain and spinal cord.
Gout.

In what cases can complications occur when using the drug "Indapamide"

Lactose intolerance.
Pregnancy and lactation period.
Age up to 18 years.
Unstable water-electrolyte balance.

Directions for use, dosage

The drug is taken orally once a day, 2.5 mg. Morning administration is more effective, since large amounts of food slow down the absorption of the medicine. The tablets should be swallowed without chewing, with plenty of water. Increasing the dose of the drug "Indapamide" does not lead to an acceleration of the therapeutic effect, but causes a number of side effects. For patients suffering from heart failure, if there is no improvement, a dose of 5 mg per day is prescribed.

Adverse reactions

When taking the drug "Indapamide" (we already know what it is prescribed for), a side effect may occur. First of all, this happens when an increased dose of the drug is used, the body is intolerant of the substance, or the effect of individual components on a certain organ system. Side effects can manifest themselves in different ways.

Central nervous system: headache, drowsiness, asthenia, insomnia, irritability.
Respiratory system: pharyngitis, acute cough.
Digestive system: nausea, vomiting, diarrhea.
Urinary system: nocturia, infectious inflammation.
Cardiovascular system: arrhythmia, rapid heartbeat, hypokalemia.
Skin diseases: itching, urticaria, rash.

Price

The average price of the drug "Indapamide" in Russia is 12 rubles. The package contains 30 tablets of 2.5 mg.

Interaction with other drugs

Anti-inflammatory drugs reduce the effect of the drug "Indapamide", quickly consume fluid in the body, which is why it has to be constantly replenished. When taking Indapamide tablets, what determines the compatibility with other medications? The composition of the diuretic is quite complex, so complex treatment is selected by a specialist strictly individually, based on the prescribed drugs.

Drugs containing lithium are rapidly excreted in the urine, so it is necessary to monitor the level of the substance in the blood serum.
GCS, on the contrary, retain water in the body, reducing the antihypotensive effect.
reduce the amount of potassium in the body, which can lead to hypokalemia.
Calcium: increases the salt content in the body.
X-ray contrast agents containing significant amounts of iodine can lead to the development of kidney failure.
Tricyclic antidepressants cause a risk of orthostatic hypotension.

special instructions

Which patients require careful monitoring of their condition while taking Indapamide? What do they need to protect themselves from? Patients with cirrhosis of the liver, heart, kidney, and liver failure are required to undergo treatment with the drug "Indapamide" strictly under the supervision of doctors. The possible appearance of dehydration in the body leads to an exacerbation of organ dysfunction. It is important to control the fluid content in the body and compensate for it in time.

24.10.2018

Doctors prescribe diuretics to patients with hypertension. They help remove excess fluid from the body.

A common drug is Indapamide. It is worth studying the instructions for use before taking the drug.

In what cases is Indapamide prescribed?

The purpose of Indapamide is the treatment of arterial hypertension. The drug is prescribed for persistent high blood pressure, which causes swelling and retains fluid in the body.

When excess fluid is removed, blood pressure normalizes (decreases).Blood pressure tablets Indapamide are a component in the treatment of hypertension. In addition to it, doctors prescribe other drugs intended to treat arterial hypertension.

What blood pressure does Indapamide help with? The drug is prescribed for high blood pressure, which leads to the development of full-fledged arterial hypertension. A harbinger of arterial hypertension is blood pressure readings of 142/105.

Indapamide is a diuretic, the main task is to remove excess fluid from the body. This drug is considered a diuretic.

If you take the medicine in large doses, it does not enhance the hypotensive effect of other drugs.At the same time, the diuretic properties are enhanced. Because of this, doctors do not recommend increasing the dosage on your own.

The price of Indapamide averages from 25 to 55 rubles.

Instructions for use and dosage

Indapamide should be taken without chewing and washed down with plenty of water. Basically, doctors prescribe one tablet per day. One tablet - 2.5 mg. If after a course of treatment, which was 1 - 2 months, the patient does not have a result, then treatment continues.

Increasing the dosage can lead to unpleasant consequences and complications. In this case, it is worth replacing Indapamide with another drug.

In the treatment complex, Indapamide is replaced with a drug that is not included in the group of diuretics and has an antihypertensive effect.

When the course of treatment consists of Indapamide Retard, the dosage of the former remains unchanged, that is, one tablet once a day. Retard – one tablet (1.5 mg) is taken once a day and washed down with plenty of water. If after two months there is no result, then Indapamide Retard is replaced with another drug, with the same conditions as in the first situation.

When a patient is prescribed treatment with two drugs, the initial dosage of Indapamide is 1.5 times a day in the morning.

Elderly patients taking Indapamide Retard are under the supervision of their attending physician. Once a month, the patient must be tested to determine plasma creatinine concentration. The patient's body weight, age and gender are taken into account. The drug is prescribed to elderly patients whose kidneys function normally.

Medicine Indapamide for hypertension

This medicine is a common way to combat high blood pressure and has a number of benefits. It easily lowers blood pressure and is harmless to the human body.

Indapamide is prescribed to all patients suffering from diabetes mellitus and vascular lesions. The drug does not affect the metabolic process, blood glucose and uric acid do not increase. These advantages allow us to consider the drug Indapamide in demand for hypertension.

Indapamide is not considered an emergency treatment for high blood pressure or hypertensive crisis.

Important! Despite the advantages of this drug, it is prescribed exclusively by the attending physician.

The first result of Indapamide appears after 7-14 days with daily use. It has a smooth effect on blood pressure. There are drugs that can quickly lower blood pressure levels than Indapamide. But such drugs have many negative consequences.

Based on the results of numerous studies, experts have determined that Indapamide is more effective if taken in combination with medications. To maintain blood pressure within 120-130/85 millimeters of mercury, doctors prescribe Indapamide with angiotensin-acting drugs.

Based on research results, it was determined that Indapamide helps reduce the risk of heart attacks, strokes and other consequences caused by hypertension.

It is easier for each patient to take one tablet a day than to swallow several of them. Preparations containing two or three active ingredients are in great demand.

If you have high blood pressure, your doctor will prescribe a combination medicine. The drug is prescribed to patients diagnosed with hypertension of the first or second degree, accompanied by edema. Edema occurs due to heart failure.

Indapamide is taken once a day, one tablet. The tablet is taken whole and washed down with water. If the patient does not have the desired result, then Indapamide is replaced with another drug. Otherwise, irreversible side effects may occur.The doctor may cancel it or prescribe another drug in addition to Indapamide.

When should you not take Indapamide?

Indapamide should not be taken by patients with:

impaired liver functions;
anuria (complete cessation of urine flow into the bladder);
allergic reaction to the active ingredients of this drug;
metabolic diseases;
impaired cerebral circulation;
reduced concentration of potassium ions in the blood;

Doctors do not recommend taking the drug to pregnant women or during breastfeeding. The active substance of the drug negatively affects intrauterine development and can cause fetal malnutrition.

If, according to indications, a woman needs to take the drug during breastfeeding, then the baby is temporarily transferred to artificial feeding.

Before prescribing Indapamide to a patient, the doctor must send him for certain tests. This is especially true when the patient has a tendency to water-salt changes.

If the doctor prescribes the drug, the patient donates blood once every two weeks so that the doctor can monitor sodium, potassium and magnesium levels in the blood plasma. The level of nitrogen residue, uric acid and glucose is controlled.

When the drug is prescribed to patients diagnosed with chronic cardiovascular failure, coronary heart disease, cirrhosis of the liver, the patient is under strict control. The patient has an increased risk of developing metabolic alkalosis and hepatic encephalopathy.

How long does the treatment last?

When patients with hypertension are prescribed antihypertensive drugs, the course of treatment lasts several weeks. After your blood pressure normalizes, you can stop taking it.

The attending physician can resolve the issue. To prevent a rebound increase in blood pressure, the patient must follow proper nutrition and all the instructions of the attending physician.

The duration of the course is determined by the doctor. Treatment may last differently for each patient. All this depends on the individual characteristics of the body and the degree of hypertension.

Side effect

If you follow all the rules for using Indapamide, you can avoid side effects. Otherwise, non-compliance with the rules may result in:

dizziness, headaches, insomnia, asthenic syndrome and other disorders of the central nervous system;
hypotension (a sharp decrease in blood pressure to below 85 millimeters of mercury), cardiac arrhythmia;
severe cough, pharyngitis (infectious disease of the larynx), sinusitis (inflammation of the mucous membrane in the nasal sinus);
various disorders of the circulatory system, changes in normal blood levels;
all kinds of allergic reactions, skin rashes and hives.

The above side effects are considered the most common, but if you follow all the rules, they can be avoided.

special instructions

If, in addition to Indapamide, the patient takes drugs to combat heart failure, a laxative, then once every two weeks it is necessary to take tests that monitor the content of potassium ion and creatinine in the blood. The doctor systematically monitors potassium, magnesium and sodium levels in the blood plasma.

Patients diagnosed with liver cirrhosis, coronary heart disease, metabolic alkalosis, chronic heart failure, as well as elderly patients are under strict medical supervision.

Patients who have an increased Q-T interval are at risk. It is determined using an electrocardiogram. This interval may be increased at birth, or may be caused by pathological processes.

The first time the doctor prescribes a test for potassium concentration in the blood a few days after treatment.

In order for the patient to remove excess fluid from the body and have normal blood pressure levels, Indapamide is taken throughout life. But, if the patient does not experience side effects.

Elevated blood calcium levels are caused by previously undiagnosed hyperparathyroidism.In patients diagnosed with diabetes, doctors monitor glucose levels.

Against the background of dehydration, renal failure develops and glomerular filtration decreases. To do this, patients compensate for the lack of fluid in the body with drugs.

To achieve the effect, patients undergo doping control. Patients with arterial hypertension should stop diuretic treatment before starting treatment. If you cannot do without diuretics, you can resume taking them later. In such situations, doctors prescribe the lowest dose inhibitors. L the drug reduces alertness and reaction, so you should not drive a car or engage in dangerous activities during the treatment period.

Interaction of Indapamide with drugs

Violation of the hypotensive effect is observed when Indapamide is taken simultaneously with high-dose salicylates and a systemic non-steroidal anti-inflammatory drug.
When a patient suffers from dehydration, Indapamide causes kidney failure. In these cases, you need to replenish the fluid.
The level of lithium in the blood may increase if you take drugs containing lithium salt with Indapamide. This occurs due to decreased excretion of elements. If the patient needs to take a complex of medications, then tests must be taken.
Glucocorticosteroid and tetracosactide drugs can neutralize the hypotensive effect. This occurs due to the retention of sodium and water ions in the body.
Drugs with laxative effects can cause hyperkalemia. If the doctor prescribes these drugs in combination, then you have to monitor the level of potassium in the blood serum to avoid the disease.
Hyperkalemia can develop due to the combination of diuretics with a diuretic drug, which conserves potassium in the body.
If Indapamide is used together with angiotensin-converting enzyme inhibitors, acute renal failure and arterial hypertension may develop.
The level of creatinine in the blood plasma may increase due to the combination of Indapamide with cyclosporine.
The use of radiocontrast agents leads to renal failure.

If you take the drug for a month and it does not give the desired results, do not increase the dose under any circumstances, otherwise serious side effects may occur.

Talk to your doctor and he will prescribe a different treatment.Indapamide is taken in combination with medications, the effect becomes pronounced.

The course of treatment with Indapamide is considered one of the long ones. You can notice the results after 10-14 days, and the maximum effect - after three months. The active substance begins to act a few hours after taking the tablet.

If you notice any adverse reactions during treatment, contact your doctor. There are two options to get rid of them:

The doctor stops this drug.
The dosage is reduced.

Doctors often use the first option, since Indapamide’s side effects are serious.